⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

July 15, 2025

Supplementary Figure 2 from The XPO1 Inhibitor Eltanexor Modulates the Wnt/β-Catenin Signaling Pathway to Reduce Colorectal Cancer Tumorigenesis

Andrew E. Evans Sahida Afroz Alexa Magstadt Anup Kasi Dan A. Dixon

View at Publisher

Ask AI

Bookmark

Share

Key Points

Eltanexor effectively reduces xpo1 protein expression in various colorectal cancer cell lines.
Treatment prevents colony formation, indicating a decrease in tumorigenesis.
The study focuses on the modulation of the wnt/β-catenin signaling pathway by eltanexor.
These findings could improve therapeutic strategies for managing colorectal cancer.

Implication

Eltanexor treatment decreases xpo1 expression and colony formation in colorectal cancer cells, suggesting a role in tumor management.

Abstract

Figure S2. Eltanexor treatment reduces XPO1 protein expression in multiple CRC cell lines and prevents colony formation.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Evans et al. (2025) studied this question.

synapsesocial.com/papers/689a02bce6551bb0af8cc72a https://doi.org/10.1158/2767-9764.29568707

View at Publisher

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure 4 from The XPO1 Inhibitor Eltanexor Modulates the Wnt/β-Catenin Signaling Pathway to Reduce Colorectal Cancer Tumorigenesis2025
2Supplementary Figure 1 from The XPO1 Inhibitor Eltanexor Modulates the Wnt/β-Catenin Signaling Pathway to Reduce Colorectal Cancer Tumorigenesis2025
3Supplementary Figure 3 from The XPO1 Inhibitor Eltanexor Modulates the Wnt/β-Catenin Signaling Pathway to Reduce Colorectal Cancer Tumorigenesis2025
4Supplementary Figure 5 from The XPO1 Inhibitor Eltanexor Modulates the Wnt/β-Catenin Signaling Pathway to Reduce Colorectal Cancer Tumorigenesis2025
5Data from The XPO1 Inhibitor Eltanexor Modulates the Wnt/β-Catenin Signaling Pathway to Reduce Colorectal Cancer Tumorigenesis2025

More related papers

Figure 1 from The XPO1 Inhibitor Eltanexor Modulates the Wnt/β-Catenin Signaling Pathway to Reduce Colorectal Cancer Tumorigenesis2025
Figure 2 from The XPO1 Inhibitor Eltanexor Modulates the Wnt/β-Catenin Signaling Pathway to Reduce Colorectal Cancer Tumorigenesis2025
Figure 6 from The XPO1 Inhibitor Eltanexor Modulates the Wnt/β-Catenin Signaling Pathway to Reduce Colorectal Cancer Tumorigenesis2025