Supplementary Figure 2 from The XPO1 Inhibitor Eltanexor Modulates the Wnt/β-Catenin Signaling Pathway to Reduce Colorectal Cancer Tumorigenesis

Key Points

• Eltanexor effectively reduces xpo1 protein expression in various colorectal cancer cell lines.
• Treatment prevents colony formation, indicating a decrease in tumorigenesis.
• The study focuses on the modulation of the wnt/β-catenin signaling pathway by eltanexor.
• These findings could improve therapeutic strategies for managing colorectal cancer.