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July 21, 2025Open Access

Dynamic shape remodeling of vesicles by internal active filaments

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Authors

ASArash Karaei ShirazABAmir Houshang Bahrami

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Overview

Non-equilibrium simulations reveal active filaments significantly influence vesicle shape and dynamics under osmotic stress, indicating new pathways for cellular structure formation.

Key Points

  • Dynamic shape remodeling of vesicles occurs due to active filaments and osmotic stress effects.
  • Simulations demonstrate vesicles can transform into branched tubes and compartmentalized structures based on filament properties.
  • Morphological changes are driven by filament concentration, mobility, stiffness, and vesicle volume variations.
  • Findings enhance understanding of cellular structures and suggest innovative methods for synthetic membrane systems.

Cite This Study

Shiraz et al. (2025) studied this question.

synapsesocial.com/papers/689a02c9e6551bb0af8cd00ehttps://doi.org/10.1101/2025.07.16.665046
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