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July 25, 2025Frontiers in ImmunologyOpen Access

Dissecting the intratumoral microbiome landscape in lung cancer

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Authors

YZYan ZhaoZYZhibo YangDWDan Wu

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Overview

This review reveals the role of the intratumoral microbiome in lung cancer, highlighting implications for immune responses and therapeutic outcomes.

Key Points

  • MAIN FINDING: The intratumoral microbiome plays a crucial role in shaping tumor behavior and treatment efficacy in lung cancer.
  • KEY EVIDENCE: Specific microbial taxa have been linked to changes in immune responses and responses to immunotherapy.
  • APPROACH: The review integrates data from molecular epidemiology and preclinical models to explore microbiome interactions.
  • SIGNIFICANCE: Understanding the microbiome's role could lead to novel biomarker discovery and enhance cancer treatment strategies.

Cite This Study

Zhao et al. (2025) studied this question.

synapsesocial.com/papers/689a0627e6551bb0af8ce250https://doi.org/10.3389/fimmu.2025.1614731
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