Literature review reveals complex cellular composition and pathophysiological implications of cardiac valves, indicating their crucial role in valve function.
Key Points
MAIN FINDING: Cardiac valves possess a complex, three-layered structure involving distinct cellular components.
KEY EVIDENCE: Valvular endothelial cells differ from vascular endothelial cells and are vital for maintaining valve function.
APPROACH: A systematic literature review analyzed the anatomy, histology, and physiology of heart valves.
SIGNIFICANCE: Understanding the cellular interplay could advance knowledge about valve pathology, aiding in future treatments.