Key result
Light and electron microscopy of all four cardiac valves from 15 dogs was performed to reassess the basic mechanisms of valve performance and potential active roles in cardiovascular regulation.
Population
15 dogs (leaflets from all four valves)
Design
Preclinical
Authors
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No immediate change to passive valve models in surgery; leaves open active neural roles pending in vivo data.
This preclinical study aimed to reassess the basic mechanisms of cardiac valve performance by analyzing valve structure in dogs using light and electron microscopy.
Theodore Cooper (1966) studied this question. Microscopic structural analysis was evaluated on Cardiac valve structure. Light and electron microscopy of all four cardiac valves from 15 dogs was performed to reassess the basic mechanisms of valve performance and potential active roles in cardiovascular regulation.
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