Design
Review
Key result
The aortic valve performs highly sophisticated functions regulated by its cellular parts, allowing adaptation to its hemodynamic and mechanical environment.
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Aortic valve exhibits active adaptive functions; extends passive models and leaves open cellular targets for valve disease research.
Understanding the cellular and molecular mechanisms of normal aortic valve physiology is essential for elucidating the mechanisms behind valve disease.
El-Hamamsy et al. (2010) conducted a review in Aortic valve physiology and disease. The aortic valve performs highly sophisticated functions regulated by its cellular parts, allowing adaptation to its hemodynamic and mechanical environment.
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