Key result
The aortic valve functions as a living, dynamic organ capable of adapting to its biomechanical environment, emphasizing the need for tissue-engineered living heart valve substitutes.
The review emphasizes the paradigm shift of viewing the aortic valve as a living, dynamic organ, underscoring the need for tissue-engineered living valve substitutes.
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Warrants further living valve engineering research; leaves open clinical superiority over existing replacements.
Chester et al. (2014) conducted a review in Aortic valve disease. Tissue-engineered heart valve substitutes was evaluated. The aortic valve functions as a living, dynamic organ capable of adapting to its biomechanical environment, emphasizing the need for tissue-engineered living heart valve substitutes.
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