Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

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Psychedelic drugs reduce inflammation and alter immune responses in animal models, suggesting new therapeutic approaches.

Psychedelic drugs can influence inflammation through modulation of immune responses.
In vivo studies show that psychedelics like (R)-DOI reduce inflammation in animal disease models.
Clinical studies indicate that psilocybin impacts cytokine levels in humans, supporting its use in therapy.
Emerging PIPI drugs may offer anti-inflammatory effects without psychedelic experiences, expanding treatment options.

Qureshi et al. (2025) studied this question.

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View Full Paper

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Psychedelic drugs reduce inflammation and alter immune responses in animal models, suggesting new therapeutic approaches.

Psychedelic drugs can influence inflammation through modulation of immune responses.
In vivo studies show that psychedelics like (R)-DOI reduce inflammation in animal disease models.
Clinical studies indicate that psilocybin impacts cytokine levels in humans, supporting its use in therapy.
Emerging PIPI drugs may offer anti-inflammatory effects without psychedelic experiences, expanding treatment options.

Qureshi et al. (2025) studied this question.

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