July 30, 2025Open Access

Mechanisms Underlying Muscle-Related Diseases and Aging: Insights into Pathophysiology and Therapeutic Strategies

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Authors

JFJialin FanRutgers, The State University of New Jersey ZKZara KhanzadaRutgers, The State University of New Jersey YXYunpeng XuRutgers, The State University of New Jersey

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Implication

This review uncovers mitochondrial dysfunction and chronic inflammation's role in muscle aging, suggesting new therapeutic strategies for enhanced muscle health.

Key Points

Skeletal muscle aging leads to loss of muscle mass and strength due to mitochondrial dysfunction.
Progressive degeneration is influenced by chronic inflammation and muscle stem cell exhaustion.
Recent advances explore both mitochondrial and non-mitochondrial mechanisms of muscle-related diseases.
Emerging therapeutic strategies aim to enhance muscle health and support healthy aging.

Cite This Study

Fan et al. (2025) studied this question.

synapsesocial.com/papers/689a0945e6551bb0af8cefdd https://doi.org/10.20944/preprints202507.2086.v1

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Implication

This review uncovers mitochondrial dysfunction and chronic inflammation's role in muscle aging, suggesting new therapeutic strategies for enhanced muscle health.

Mechanisms Underlying Muscle-Related Diseases and Aging: Insights into Pathophysiology and Therapeutic Strategies

Discussion

Member takes

Implication

Key Points

Cite This Study

Mechanisms Underlying Muscle-Related Diseases and Aging: Insights into Pathophysiology and Therapeutic Strategies

Discussion

Member takes

Implication

Key Points

Cite This Study

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