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July 31, 2025Frontiers in Public HealthOpen Access

Assessment of ovarian dysfunction induced by environmental toxins: a systematic review

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Authors

LALei AnYHYa-Li HuangYWYunkai Wang

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Overview

Systematic review reveals environmental pollutants negatively affect ovarian reserve in women, highlighting reproductive toxicity implications.

Key Points

  • Pollutants like PFAS, PCBs, and PM2.5 significantly harm ovarian function, particularly in younger women under 35.
  • Long-term exposure to particulate matter is linked to a notable decrease in ovarian reserve, measured by anti-Müllerian hormone levels.
  • Forty cohort studies evaluated the impact of 20 types of pollutants on ovarian health, indicating serious reproductive risks.
  • Challenges in evidence synthesis and methodological limitations necessitate further research to validate these findings.

Cite This Study

An et al. (2025) studied this question.

synapsesocial.com/papers/689a094be6551bb0af8cf46chttps://doi.org/10.3389/fpubh.2025.1575418
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mitigation of Environmental Exposure, Pollutants, and Endocrine Disruptors to Reproductive Health: A Literature Review2025 · 2 citations
  2. 2Environmental Pollution, Endocrine Disruptors, and Metabolic Status: Impact on Female Fertility—A Narrative Review2025
  3. 3FIGO Committee Opinion: Environmental Drivers of Gynecologic and Reproductive Health2025
  4. 4Mechanisms by which “Everywhere” and “Forever” Environmental Chemicals Impact Ovarian Function and Female Fertility2026
  5. 5Reproductive toxicology of environmental endocrine-disrupting chemicals in women: a cohort study protocol2024 · 4 citations