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August 1, 2025

Table S3 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma

Tiankai Xie Josey C. Sorenson Logan G. Spector Nathan Pankratz R. Stephanie Huang Eiso Hiyama Jenny N. Poynter Gail E. Tomlinson Carolina Armengol Roland Kappler Michael E. Scheurer Eve Roman Aurora Castellano Michael A. Grotzer David S. Ziegler Saonli Basu Erin L. Marcotte Tianzhong Yang

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Key Points

The study identifies candidate genes linked to hepatoblastoma using fine mapping techniques on chr 11.
Findings suggest that genes associated with the disease may vary across different ancestries, particularly in European populations.
The fine mapping approach utilized a window size of 250kb to enhance the accuracy of gene identification.
These insights into genetic factors may lead to improved understanding and treatment strategies for hepatoblastoma.

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Implication

Transcriptome-wide association study identifies candidate genes associated with hepatoblastoma, implying genetic links across populations.

Abstract

Fine mapping results of putative genes on chr 11 for European ancestry-based TWAS results with window size 250kb

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Cite This Study

Xie et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d010a https://doi.org/10.1158/1055-9965.29762026

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Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S4 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
2Table S11 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
3Table S10 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
4Table S12 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
5Figure S1 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
6Table S7 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
7Table S2 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
8Table S4 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025