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August 1, 2025

Figure S1 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma

Tiankai Xie Josey C. Sorenson Logan G. Spector Nathan Pankratz R. Stephanie Huang Eiso Hiyama Jenny N. Poynter Gail E. Tomlinson Carolina Armengol Roland Kappler Michael E. Scheurer Eve Roman Aurora Castellano Michael A. Grotzer David S. Ziegler Saonli Basu Erin L. Marcotte Tianzhong Yang

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Key Points

MAIN FINDING: This study identifies candidate genes associated with hepatoblastoma using multiancestry data.
KEY EVIDENCE: The analysis includes QQ plots for SNPs with minor allele frequency greater than 0.05, highlighting critical variants.
APPROACH: A transcriptome-wide association study evaluated SNPs among three ancestries to determine genetic associations.
SIGNIFICANCE: Understanding the genetic factors in hepatoblastoma may lead to improved screening and treatment strategies.

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Implication

Multiancestry analysis identifies significant SNPs linked to hepatoblastoma, suggesting genetic factors across populations.

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Cite This Study

Xie et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d012c https://doi.org/10.1158/1055-9965.29762086

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Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S4 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
2Table S3 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
3Table S12 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
4Table S11 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
5Table S7 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
6Table S10 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
7Figure S2 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
8Figure S6 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025