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August 1, 2025

Table S10 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma

Tiankai Xie Josey C. Sorenson Logan G. Spector Nathan Pankratz R. Stephanie Huang Eiso Hiyama Jenny N. Poynter Gail E. Tomlinson Carolina Armengol Roland Kappler Michael E. Scheurer Eve Roman Aurora Castellano Michael A. Grotzer David S. Ziegler Saonli Basu Erin L. Marcotte Tianzhong Yang

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Key Points

MAIN FINDING: The research identifies novel candidate genes associated with hepatoblastoma through a transcriptome-wide approach.
KEY EVIDENCE: Analysis of curated single-cell RNA data revealed significant associations with genes linked to hepatoblastoma.
APPROACH: The study utilized a multiancestry transcriptome-wide association framework to explore genetic links.
SIGNIFICANCE: These findings may pave the way for improved understanding and potential treatment strategies for hepatoblastoma.

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Implication

Association study uncovers candidate genes related to hepatoblastoma, suggesting new research avenues.

Abstract

Curated single-cell RNA data for the discovered genes from Descartes

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Cite This Study

Xie et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d0118 https://doi.org/10.1158/1055-9965.29762041

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Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context:

1Table S12 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
2Table S11 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
3Figure S4 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
4Table S3 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
5Table S7 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
6Figure S10 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
7Figure S1 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
8Figure S2 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025