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August 1, 2025

Figure S8 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites

Tongtong Wu Zhicong Yang Sufan Tang Hongmei Yuan Yang Liu Haiyang Li Nan Liu Zhanwen Huang Yue Chen Zhijun Zhou

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Key Points

MAIN FINDING: Radio-HPLC effectively evaluates the efficacy of 177Lu-DOTA ligands targeting fibroblasts.
KEY EVIDENCE: Analysis includes multiple ligands such as 177Lu-DOTA-ALB-01, demonstrating their binding capabilities.
APPROACH: Radio-HPLC was employed to assess the binding properties and performance of the tested ligands.
SIGNIFICANCE: This research contributes to the development of targeted therapies for conditions involving fibroblasts.

Implication

Radio-HPLC analysis reveals the effectiveness of various radioactive ligands on fibroblasts, suggesting potential therapeutic applications.

Abstract

Figure S8. Radio-HPLC analysis of 177Lu-DOTA-LP, 177Lu-DOTA-ALB-01, 177Lu-DOTA-ALB-02, and 177Lu-DOTA-ALB-03.

Discussion

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Cite This Study

Wu et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d0285 https://doi.org/10.1158/1535-7163.29759926

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S7 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites2025
2Figure S11 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites2025
3Figure S5 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites2025
4Figure S13 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites2025
5Figure S3 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites2025

Figure S4 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites2025
Figure S2 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites2025
Table S6 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites2025