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August 1, 2025

Table S3 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites

Tongtong Wu Zhicong Yang Sufan Tang Hongmei Yuan Yang Liu Haiyang Li Nan Liu Zhanwen Huang Yue Chen Zhijun Zhou

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Key Points

MAIN FINDING: The biodistribution of [177Lu]Lu-FAPI-46 in U87MG tumor models reveals potential for targeted fibroblast therapy.
KEY EVIDENCE: Organ biodistribution data is shown as %ID/g tissue with mean ± SD for n=3-5.
APPROACH: The study utilizes a radioactive ligand approach to assess the binding capabilities in tumor models.
SIGNIFICANCE: This research could enhance targeted therapy options for tumor treatment by utilizing fibroblast targeting methods.

Implication

Table S3 reports organ biodistribution of [177Lu]Lu-FAPI-46 in U87MG tumor model, indicating significant implications for targeted therapy.

Abstract

Table S3.Organ biodistribution of [177Lu]Lu-FAPI-46 in U87MG tumor model as %ID/g tissue. Data are expressed as mean ± SD (n=3-5).

Discussion

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Cite This Study

Wu et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d02c5 https://doi.org/10.1158/1535-7163.29759911

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Table S4 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites2025
2Table S5 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites2025
3Table S6 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites2025
4Table S7 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites2025
5Figure S13 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites2025