Figure 3 from Defining the Ovarian Cancer Precancerous Landscape through Modeling Fallopian Tube Epithelium Reprogramming Driven by Extracellular Vesicles

Transcriptomics analysis of hFTE after short-term EV exposure (1 day). A and B, Volcano plots showing differentially expressed transcripts in secretory cells in (A) OVCAR3 EV–treated and (B) FT240 EV–treated hFTE compared with PBS controls. C and D, Volcano plots showing differentially expressed transcripts in ciliated cells in (C) OVCAR3 EV–treated and (D) FT240 EV–treated hFTE compared with PBS controls. E and F, Venn diagrams comparing DEGs induced in (E) secretory cells and (F) ciliated cells by OVCAR3 EV treatment compared with FT240 EV treatment.