August 4, 2025

Figure S3 from Modeling High-Risk Pediatric Cancers in Zebrafish to Inform Precision Therapy

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MAIN FINDING: Pediatric cancers can be effectively modeled in zebrafish, providing insights into their growth and treatment response.
KEY EVIDENCE: Analysis of tumor growth curves demonstrates distinct patterns that correlate with performance in precision therapy.
APPROACH: Tumor growth and Kaplan-Meier survival curves were generated from mouse PDX models to compare with zebrafish data.
SIGNIFICANCE: This approach may enhance the understanding of pediatric cancers, guiding personalized treatment strategies for better outcomes.

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Modeling pediatric cancers in zebrafish reveals tumor growth dynamics and survival trends, suggesting pathways for precision therapy.

Mouse PDX tumor growth curves and Kaplan-Meier survival curves

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Azzam et al. (2025) studied this question.

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Modeling pediatric cancers in zebrafish reveals tumor growth dynamics and survival trends, suggesting pathways for precision therapy.

Mouse PDX tumor growth curves and Kaplan-Meier survival curves