August 4, 2025

Table S1 from Modeling High-Risk Pediatric Cancers in Zebrafish to Inform Precision Therapy

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MAIN FINDING: The research demonstrates how larval zebrafish PDX models can inform precision therapy for pediatric cancers.
KEY EVIDENCE: Treatments involved single agent and combination doses administered over 72 hours post-fertilization.
APPROACH: Study utilized larval zebrafish at 35°C for 3 to 7 days to establish effective drug dosages.
SIGNIFICANCE: Insights from zebrafish models may enhance treatments and therapy effectiveness for high-risk pediatric cancers.

Implication

Research reveals treatment impact on pediatric cancers in zebrafish PDX models, suggesting insights for precision therapy.

Abstract

Single agent and combination doses established in the larval zebrafish PDX at 35°C for 3 to 7 days post fertilization zebrafish for 72-hour treatment.

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Cite This Study

Azzam et al. (2025) studied this question.

synapsesocial.com/papers/689a0f8de6551bb0af8d0de7 https://doi.org/10.1158/2767-9764.29644672

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Implication

Research reveals treatment impact on pediatric cancers in zebrafish PDX models, suggesting insights for precision therapy.

Abstract

Single agent and combination doses established in the larval zebrafish PDX at 35°C for 3 to 7 days post fertilization zebrafish for 72-hour treatment.

Table S1 from Modeling High-Risk Pediatric Cancers in Zebrafish to Inform Precision Therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

Table S1 from Modeling High-Risk Pediatric Cancers in Zebrafish to Inform Precision Therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

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