August 4, 2025

Table S2 from Modeling High-Risk Pediatric Cancers in Zebrafish to Inform Precision Therapy

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MAIN FINDING: Pediatric cancers can be modeled effectively in zebrafish to enhance precision therapy approaches.
KEY EVIDENCE: Features of mouse PDX and larval zebrafish PDX models were compared to standard in vitro models.
APPROACH: The study analyzed various modeling systems, focusing on their relevance for high-risk pediatric cancers.
SIGNIFICANCE: Advances in modeling could lead to more personalized and effective therapies for pediatric cancer patients.

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Modeling techniques show differences in PDX and in vitro models for high-risk pediatric cancers, indicating potential for improved therapies.

Features of mouse PDX, larval zebrafish PDX and in vitro models

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Azzam et al. (2025) studied this question.

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Modeling techniques show differences in PDX and in vitro models for high-risk pediatric cancers, indicating potential for improved therapies.

Features of mouse PDX, larval zebrafish PDX and in vitro models