Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 5, 2025ACS Applied Bio Materials

Nanomaterial-Mediated Nucleic Acid Delivery for Pancreatic Cancer Therapeutics

View Full Paper
Ask AI
Bookmark
Share

Authors

UNUrmica NandyAMAbul Kalam Azad MandalPTPranav Tiwari

Discussion

Loading...

Member takes

Overview

Review reveals nanomaterial-enhanced delivery of nucleic acid therapeutics in pancreatic cancer, highlighting 3D models' relevance.

Key Points

  • Nucleic acid therapeutics provide a promising alternative to traditional pancreatic cancer treatments.
  • Nanomaterials serve as effective carriers, enhancing delivery and targetability of therapeutic agents like siRNA and mRNA.
  • The review compares preclinical assessments of various nanocarriers in wild-type and drug-resistant pancreatic cancer cells.
  • Three-dimensional cell culture models show advantages over two-dimensional models for nucleic acid delivery in practical applications.

Cite This Study

Nandy et al. (2025) studied this question.

synapsesocial.com/papers/689a0f99e6551bb0af8d145bhttps://doi.org/10.1021/acsabm.5c00968
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Breaking barriers: nano-boosted drug delivery systems in overcoming the defenses of pancreatic cancer2026
  2. 2Beyond chemotherapy: The rise of nucleic acid nanoformulations in personalized lung cancer therapy2026
  3. 3Advances in Nucleic Acid Delivery Using Nanocarriers for Gene Therapy in Cancer: A Narrative Review.2026
  4. 4Micelleplex nucleic acid delivery systems: Overcoming barriers for treatment of advanced solid tumors2025 · 6 citations
  5. 5Nanocarrier-Based Strategies for Advanced Cancer Drug Delivery and Therapeutics: Design Principles, Biological Interactions, and Clinical Potential2026 · 12 citations