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August 7, 2025Frontiers in ImmunologyOpen Access

The impact of enteral immunonutrition on gut microbiota in colorectal cancer and gastric cancer patients in the preoperative period—preliminary results of randomized clinical trial

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Authors

KKKarolina Kaźmierczak-SiedleckaESEwa StachowskaRKRobert Kucharski

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Overview

Randomized clinical trial showed no significant changes in gut microbiota of colorectal and gastric cancer patients, suggesting limited effects of immunonutrition.

Key Points

  • MAIN FINDING: Immunonutrition did not significantly alter gut microbiota in colorectal and gastric cancer patients before surgery.
  • KEY EVIDENCE: Statistical analysis showed no significant differences in alpha diversity indices between dietary groups.
  • APPROACH: Fourteen patients received either immunonutrition or standard products for seven days before surgery.
  • SIGNIFICANCE: Understanding immunonutrition's role in gut microbiota may inform nutritional support in cancer care.

Cite This Study

Kaźmierczak-Siedlecka et al. (2025) studied this question.

synapsesocial.com/papers/689dfe88d61984b91e13b7fehttps://doi.org/10.3389/fimmu.2025.1606187
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