August 7, 2025GeriatricsOpen Access

Effect of Anti-Diabetic Medication Use on Sepsis Risk in Type 2 Diabetes Mellitus: A Multivariate Analysis

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Main finding indicates insulin-treated patients face a 2.6-fold higher sepsis risk compared to those on other medications.
SGLT2 inhibitors and GLP-1 receptor agonists were shown to significantly reduce sepsis risk in T2DM patients.
The analysis utilized clinical registry data from 5009 T2DM patients, employing multivariate logistic regression for robust insights.
This research highlights the need for tailored diabetes management strategies to minimize infection risks in vulnerable populations.

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Longitudinal cohort study explores sepsis risk factors in T2DM, indicating insulin use heightens risk while SGLT2 and GLP-1 medications may protect.

Ulambayar et al. (2025) studied this question.

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Longitudinal cohort study explores sepsis risk factors in T2DM, indicating insulin use heightens risk while SGLT2 and GLP-1 medications may protect.