August 7, 2025PLoS ONEOpen Access

Variability of test parameters from mice of different age groups in published data sets

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BABernhard AignerUniversity of Veterinary Medicine Vienna

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Implication

Retrospective analysis reveals phenotypic variability in test parameters across age groups of genetically identical mice, highlighting unexpected interactions in traits.

Key Points

The study identifies phenotypic variability in genetically identical mice between early and late adults.
Analysis focused on morphological, blood, and behavioral parameters from various data sets of C57BL/6N mice.
The coefficient of variation was calculated to compare variations between young and old groups of mice.
Findings show higher variability in traits like body weight and hematology in late adults, particularly in females.

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Bernhard Aigner (2025) studied this question.

synapsesocial.com/papers/689dfea6d61984b91e13c76d https://doi.org/10.1371/journal.pone.0329357

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Implication

Retrospective analysis reveals phenotypic variability in test parameters across age groups of genetically identical mice, highlighting unexpected interactions in traits.

Variability of test parameters from mice of different age groups in published data sets

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Cite This Study

Variability of test parameters from mice of different age groups in published data sets

Discussion

Member takes

Implication

Key Points

Cite This Study

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