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August 12, 2025

Retinal Neuronal Changes and Kidney Dysfunction in Diabetes Mellitus.

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Authors

DCDan CaoQYQianhui YangYHYueheng Hong

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Overview

Cross-sectional study reveals significant association between retinal layer thickness and kidney function in type 2 diabetes, suggesting potential biomarkers for diabetic kidney disease.

Key Points

  • A significant association exists between outer plexiform layer thickness and kidney function indicators in type 2 diabetes.
  • Perifoveal outer plexiform layer thickness showed the strongest inverse relationship with estimated glomerular filtration rate.
  • The study analyzed 410 type 2 diabetes patients using optical coherence tomography for retinal layer measurements.
  • Findings indicate that outer plexiform layer thickening could be a valuable biomarker for diabetic kidney disease.

Cite This Study

Cao et al. (2025) studied this question.

synapsesocial.com/papers/689e03d9d61984b91e13cccehttps://doi.org/10.1111/ceo.14592
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Optical coherence tomographic retinal differences across stages of chronic kidney disease2026
  2. 2Early choroidal and retinal changes detected by swept-source oct in type 2 diabetes and their association with diabetic kidney disease: a longitudinal prospective study2024 · 5 citations
  3. 3Ocular biomarkers in diabetes mellitus with diabetic kidney disease: A minireview2025 · 1 citations
  4. 4Evaluation of thickness of individual macular retinal layers in diabetic eyes from optical coherence tomography2024 · 5 citations
  5. 5Assessment of Retinal Nerve Fiber Layer Changes in Patients With Chronic Kidney Disease: A Cross-Sectional Study2026