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August 16, 2025

Cross-cohort microbiome-wide study reveals consistent alterations in the gut bacteriome, but not the gut mycobiome, in patients with hypertension.

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Authors

YGYidan GaoQilu Normal University DWDangrang WangDalian Medical University TLTong LuThird Affiliated Hospital of Southern Medical University

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Implication

Cross-cohort analysis reveals significant changes in the gut bacteriome but not in the mycobiome of hypertensive patients, implying new diagnostic possibilities.

Key Points

Gut bacterial diversity significantly reduced in hypertensive patients compared to controls, suggesting a potential link with hypertension risk.
The analysis identified 61 bacterial species with different relative abundances between patients and healthy individuals, indicating specific microbial alterations.
Metagenome-wide analysis utilized fecal samples from hypertensive patients and healthy controls across two regions, reinforcing the robustness of findings.
These results may enhance early diagnostic strategies for hypertension, highlighting the relevance of gut microbiota in cardiovascular health.

Cite This Study

Gao et al. (2025) studied this question.

synapsesocial.com/papers/68a26d256226934df6fbfc0b https://doi.org/10.1128/msystems.00657-25

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Implication

Cross-cohort analysis reveals significant changes in the gut bacteriome but not in the mycobiome of hypertensive patients, implying new diagnostic possibilities.

Cross-cohort microbiome-wide study reveals consistent alterations in the gut bacteriome, but not the gut mycobiome, in patients with hypertension.

Discussion

Member takes

Implication

Key Points

Cite This Study

Cross-cohort microbiome-wide study reveals consistent alterations in the gut bacteriome, but not the gut mycobiome, in patients with hypertension.

Discussion

Member takes

Implication

Key Points

Cite This Study

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