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August 15, 2025Seminars in Ophthalmology

Chronic Ocular Sequelae of Stevens-Johnson Syndrome: Recent Advances in Understanding of Patho-Physiology and Management

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Authors

PNPurvasha NarangAll India Institute of Medical Sciences RaipurSDSharon D’SouzaNarayana Nethralaya

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Implication

Observational analysis reveals chronic ocular complications in patients with Stevens-Johnson syndrome, suggesting ongoing need for management strategies.

Key Points

  • Chronic ocular complications affect up to 75% of patients with Stevens-Johnson syndrome, impairing vision significantly.
  • Key issues include dry eye disease, limbal stem cell deficiency, and conjunctival cicatrization, which can worsen over time.
  • Assessment of these ocular sequelae highlights the importance of ongoing management and surveillance in affected patients.
  • Early intervention may prevent progressive deterioration, underscoring the need for comprehensive eye care protocols.

Cite This Study

Narang et al. (2025) studied this question.

synapsesocial.com/papers/68a3654c0a429f797332ae79https://doi.org/10.1080/08820538.2025.2545264
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Lid Margin Microbiome in Stevens-Johnson Syndrome Patients With Lid Margin Keratinization and Severe Dry Eye Disease2024 · 15 citations
  2. 2Ocular involvement in Steven-Johnson syndrome/toxic epidermal necrolysis: recent insights into pathophysiology, biomarkers, and therapeutic strategies2024 · 5 citations
  3. 3Cataract surgery in chronic Stevens–Johnson syndrome: aspects and outcomes2016 · 18 citations
  4. 4Conjunctival inflammation in the chronic phase of Stevens-Johnson syndrome2000 · 53 citations
  5. 5Japan: Diagnosis and Management of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis With Severe Ocular Complications2021 · 20 citations