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September 10, 2025Seminars in Ophthalmology

Ocular Complications in stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Comprehensive Review

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Authors

KHKiana HassanpourHAHassan AsadigandomaniSSSahel Soltani Shahgoli

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Overview

This comprehensive review discusses ocular complications and management strategies in SJS/TEN, highlighting early interventions.

Key Points

  • Ocular complications are reported in up to 75% of SJS/TEN patients in the acute phase, leading to significant visual impairment.
  • Early interventions, including lubrication and amniotic membrane transplantation, effectively mitigate long-term damage.
  • Chronic complications may include limbal stem cell deficiency and severe dry eye syndrome, requiring ongoing management.
  • Timely ophthalmologic intervention is crucial, yet further research is needed to establish standardized treatment protocols.

Cite This Study

Hassanpour et al. (2025) studied this question.

synapsesocial.com/papers/68c1d22854b1d3bfb60f77ffhttps://doi.org/10.1080/08820538.2025.2548869
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Systematic Review of Ophthalmic Management and Treatment2025
  2. 2Chronic Ocular Sequelae of Stevens-Johnson Syndrome: Recent Advances in Understanding of Patho-Physiology and Management2025
  3. 3Chronic Ocular Complications in Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis: Clinical Features and Surgical Management in a Brazilian Tertiary Center2025
  4. 4Ocular involvement in Stevens–Johnson syndrome and toxic epidermal necrolysis: A review of current management and changing trends2025
  5. 5Ocular involvement in Stevens–Johnson syndrome and toxic epidermal necrolysis: A review of current management and changing trends2025