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September 12, 2025VisionOpen Access

Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Systematic Review of Ophthalmic Management and Treatment

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Authors

KSKorolos SawiresBTBrendan TaoHNHarrish Nithianandan

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Overview

Systematic review reveals treatment outcomes in ocular SJS and TEN, suggesting the need for standardized care.

Key Points

  • Best-corrected visual acuity improved in 52.2% of treated eyes, highlighting significant treatment impact.
  • Epithelial regeneration occurred in 16.8% of cases, indicating potential for positive recovery outcomes.
  • Common treatments include amniotic membrane transplantation and topical therapy, underscoring successful strategies.
  • Further prospective studies are essential to standardize care and enhance visual outcomes for patients.

Cite This Study

Sawires et al. (2025) studied this question.

synapsesocial.com/papers/68d46cc631b076d99fa68cbdhttps://doi.org/10.3390/vision9030078
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Ocular Complications in stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Comprehensive Review2025
  2. 2Ocular involvement in Stevens–Johnson syndrome and toxic epidermal necrolysis: A review of current management and changing trends2025
  3. 3Ocular involvement in Stevens–Johnson syndrome and toxic epidermal necrolysis: A review of current management and changing trends2025
  4. 4Chronic Ocular Complications in Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis: Clinical Features and Surgical Management in a Brazilian Tertiary Center2025
  5. 5Chronic Ocular Sequelae of Stevens-Johnson Syndrome: Recent Advances in Understanding of Patho-Physiology and Management2025