Clinical impact and safety of continuous renal replacement therapy in critically ill patients with solid tumors and acute kidney injury: a retrospective cohort analysis

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CRRT significantly improved AKI remission and metabolic parameters, leading to better outcomes in patients with solid tumors and acute kidney injury.
After propensity score matching, the CRRT group showed higher 90-day survival rates at 47.52% compared to 39.01% in the non-CRRT group.
Analyses using XGBoost machine learning yielded AUCs of 0.78 for mortality prediction and 0.75 for AKI remission.
The findings support the use of CRRT in this high-risk population, indicating it provides effective renal recovery with an acceptable safety profile.

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Retrospective cohort analysis demonstrates improved AKI remission and survival in ICU patients, suggesting CRRT is effective and safe.

Luo et al. (2025) studied this question.

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