Monte Carlo simulations reveal r=0.75 improves variance estimates in repeated-measures meta-analysis without raw data.
In repeated-measures meta-analyses, raw data are often unavailable, preventing the calculation of the correlation coefficient r between pre- and post-intervention values. As a workaround, many researchers adopt a heuristic approximation of r = 0.7. However, this value lacks rigorous mathematical justification and may introduce bias into variance estimates of pre/post-differences. We employed Monte Carlo simulations (n = 500,000 per scenario) in Fisher z-space to examine the distribution of the standard deviation of pre-/post-differences (σD) under varying assumptions of r and its uncertainty (σr). Scenarios included r = 0.5, 0.6, 0.707, 0.75, and 0.8, each tested across three levels of variance (σr = 0.05, 0.1, and 0.15). The approximation of r = 0.75 resulted in a balanced estimate of σD, corresponding to a “midway” variance attenuation due to paired data. This value more accurately offsets the deficit caused by assuming a correlation, compared to the traditional value of 0.7. While the r = 0.7 heuristic remains widely used, our results support the use of r = 0.75 as a more mathematically neutral and empirically defensible alternative in repeated-measures meta-analyses lacking raw data.
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Vasileios Papadopoulos (2025) studied this question.
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