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This is a Observational study (also classified as: In Vitro Study).

August 17, 2025Open Access

Human Papillomavirus Prevalence in the Prostate and Seminal Vesicles: Does This Virus Have an Etiological Role in the Development of Prostate Cancer?

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HPV-DNA was detected in 9.6% of prostate cancers, indicating possible involvement in prostate cancer development.
High-risk HPV was found in 4.5% of samples, with HPV44 being the most common genotype, showing clear prevalence trends.
Analysis included formalin-fixed tissues from 157 prostate cancer patients, using various detection methods for HPV.
Findings imply that while HPV may contribute to carcinogenesis, p16INK4a may not reliably indicate E7 gene expression.

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Analysis reveals HPV-DNA in 9.6% of prostate cancer cases, suggesting a link between high-risk HPV and tumor development.

Shinzawa et al. (2025) studied this question.

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