September 28, 2025VirusesOpen Access

Human Papillomavirus Prevalence in the Prostate and Seminal Vesicles: Does This Virus Have an Etiological Role in the Development of Prostate Cancer?

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Discussion

Analysis reveals HPV-DNA presence in 9.6% of prostate cancer lesions, suggesting a possible etiological role.

HPV-DNA detection in 9.6% of prostate cancers indicates potential involvement in carcinogenesis.
High-risk HPV was identified in 4.5% of samples, primarily in high-grade prostate cancer cases.
Genotyping showed HPV44 as the most prevalent type, while p16INK4a expression was weak or absent.
HPV infection may contribute to prostate cancer development, but its role requires further investigation.

Shinzawa et al. (2025) studied this question.

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