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August 17, 2025Open Access

Effects of Polychlorinated Biphenyls on the Peripheral and Central Auditory Systems

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Authors

NSNathiya Vaithiyalingam Chandra SekaranUniversity of Illinois Urbana-ChampaignSSSusan L. SchantzUniversity of Illinois Urbana-ChampaignDLDaniel A. LlanoCarle Foundation Hospital

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Implication

This review finds PCB exposure is linked to auditory deficits in children, suggesting risks of developmental impairment.

Key Points

  • Exposure to polychlorinated biphenyls (PCBs) during critical developmental windows can lead to lasting auditory impairments.
  • Evidence from human and animal studies shows that PCB effects on auditory function include dysfunction in cochlear outer hair cells.
  • Research indicates alterations in central auditory structures, with possible central vulnerabilities apparent even with normal auditory brainstem responses.
  • These findings underscore the need for better understanding of PCB-induced auditory impacts that can inform public health policies.

Cite This Study

Sekaran et al. (2025) studied this question.

synapsesocial.com/papers/68a36c270a429f797332fe4fhttps://doi.org/10.20944/preprints202508.0687.v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Polychlorinated Biphenyls and Its Effects on the Environment: A Brief Review2025
  2. 2Long-term effects of polychlorinated biphenyls: Neuropsychological outcomes of a longitudinal cohort study2026
  3. 3Polychlorinated Biphenyls, Oxidative Stress, and Brain Health: Mechanistic Links to Neurodegenerative and Neurodevelopmental Diseases2026 · 5 citations
  4. 4A comprehensive review on polychlorinated biphenyls in water, air and their impact on aquatic, terrestrial animals and humans2025
  5. 5A comprehensive review on polychlorinated biphenyls in water, air and their impact on aquatic, terrestrial animals and humans2025