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August 19, 2025Internal Medicine JournalOpen Access

Neurological manifestations of chronic graft versus host disease

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Authors

TKTal Jonatan KorenAKAlvin C. KwokWSWilliam Stevenson

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Overview

Retrospective analysis identifies neurological complications in 3.1% of chronic gvhd patients post allo-hsct, highlighting diagnostic challenges.

Key Points

  • Neurological complications arise in 3.1% of patients with chronic gvhd after allo-hsct, emphasizing the need for awareness in clinical practice.
  • Out of 455 allo-hsct cases reviewed, 228 presented with chronic gvhd, with four cases illustrating specific neurological disorders.
  • Retrospective analysis involved examining chronic gvhd patients, focusing on their unique neurological manifestations post-transplant.
  • Understanding the differences between chronic gvhd-related neurological disorders and idiopathic conditions can aid in better management approaches.

Cite This Study

Koren et al. (2025) studied this question.

synapsesocial.com/papers/68af4754ad7bf08b1ead3ff9https://doi.org/10.1111/imj.70184
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation2024
  2. 2Severe brain atrophy after allogeneic hematopoietic stem cell transplantation in a patient suffering from chronic graft-versus-host disease2026
  3. 3Proposal for Diagnostic Criteria for Manifestations of Chronic Graft-versus-Host Disease in Peripheral Nervous System and Muscles2026
  4. 4Proposal for Diagnostic Criteria for Manifestations of Chronic Graft-versus-Host Disease in the Central Nervous System2025
  5. 5Cerebrospinal fluid profile associated with the incidence and outcomes of patients with chronic graft-versus-host disease after haploidentical hematopoietic stem cell transplantation2025