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Real-world experience with the use of diazoxide among people living with congenital hyperinsulinism and their caregivers

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A significant 37% of participants on diazoxide reported experiencing hypoglycemia several times per week, affecting daily life.
93% of individuals using diazoxide reported side effects, with hypertrichosis being the most common at 89%.
This mixed-methods study combined quantitative data from 165 participants with qualitative insights from 18 individuals and caregivers.
The findings highlight the need for improved treatment strategies and adherence to the International HI Care Guideline to optimize therapy.

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Mixed-methods analysis reveals numerous side effects and hypoglycemia in individuals with congenital hyperinsulinism and their caregivers.

Pasquini et al. (2025) studied this question.

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Mixed-methods analysis reveals numerous side effects and hypoglycemia in individuals with congenital hyperinsulinism and their caregivers.