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This is a In Vitro Study study.

Eco-Friendly Microwave-Assisted Synthesis of Fused Pyrimido4,5-d Pyrimidine Derivatives via a Catalyst-Free Hantzsch Multicomponent Reaction

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Microwave-assisted synthesis of fused pyrimido derivatives shows high yields in green chemistry applications, emphasizing efficiency and safety.

The synthesis of fused pyrimido derivatives achieved high yields without a catalyst, demonstrating efficiency in green chemistry principles.
The one-pot Hantzsch reaction involved bis-aldehydes, barbituric acid, and substituted amines, completed under microwave irradiation.
This method highlights the advantages of operational simplicity and environmental friendliness in chemical processes.
Effective synthesis under harsh conditions isn't required, suggesting safer alternative processes for producing bi- and tri-cyclic compounds.

Elshimaa M. Eid (2025) studied this question.

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View Full Paper

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Authors

Microwave-assisted synthesis of fused pyrimido derivatives shows high yields in green chemistry applications, emphasizing efficiency and safety.

The synthesis of fused pyrimido derivatives achieved high yields without a catalyst, demonstrating efficiency in green chemistry principles.
The one-pot Hantzsch reaction involved bis-aldehydes, barbituric acid, and substituted amines, completed under microwave irradiation.
This method highlights the advantages of operational simplicity and environmental friendliness in chemical processes.
Effective synthesis under harsh conditions isn't required, suggesting safer alternative processes for producing bi- and tri-cyclic compounds.

Elshimaa M. Eid (2025) studied this question.

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