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August 21, 2025Open Access

Age and Learning Shapes Sound Representations in Auditory Cortex During Adolescence

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Authors

BPBenedikt PraegelHebrew University of JerusalemFCFeng ChenBGI Group (China)ADAdria DymEdmond and Lily Safra Children's Hospital

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Overview

Electrophysiological analysis shows lower auditory discrimination in adolescents, highlighting age and learning influence.

Key Points

  • Adolescent mice demonstrated significantly lower auditory discrimination performance compared to adults.
  • Neuronal responses in adolescents showed higher variability and slower cortical decoding during difficult tasks.
  • Electrophysiological recordings revealed distinct differences in neural representations post-learning.
  • The findings emphasize ongoing development of cognitive control mechanisms and cortical plasticity during adolescence.

Cite This Study

Praegel et al. (2025) studied this question.

synapsesocial.com/papers/68af56faad7bf08b1eadd408https://doi.org/10.7554/elife.106387.3
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