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Formulation improves bioavailability of levofloxacin in ocular applications, suggesting better patient compliance.
Levofloxacin in situ gel is developed to overcome issues associated with traditional eye drops and to enhance their bioavailability. The low bioavailability of standard eye drops is primarily due to various precorneal loss factors. Additionally, this gel offers improved patient compliance through easier application and reduces the need for frequent instillations.
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Kumari et al. (2025) studied this question.
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