Figure 5 from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis

Complement system proteins of plasma from TB mice compared with similarly aged non-TB mice. A, Heatmap representing unsupervised clustering of complement system components in TB mice (red bottom bar) vs. tumor-free mice at termination (blue bottom bar). Unsupervised clustering using Euclidian distance and Ward.D.2. B, Differential expression of complement C1q family members, a, b, and c, in TB treated as indicated. Bars represent means (n = 4) and SE. Statistical significance between treatment groups for each complement component defined by a two-way ANOVA is denoted by asterisks above the bars. *, P < 0.05; **, P < 0.01.