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August 22, 2025Open Access

Figure 4 from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis

Tina Akbarzadeh Lin Ma Jingyun Lee Jade Moore William S. Chou Siyavash Shabani Cristina M. Furdui Bahram Parvin Mary Helen Barcellos‐Hoff

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Key Points

Significantly differentially expressed proteins were identified through plasma proteomic analysis, indicating treatment efficacy.
C4b-binding protein levels varied significantly across time and treatment conditions, highlighting notable changes.
Analysis involved multiple treatment groups including sham, IR, and aspirin, with robust statistical validation procedures employed.
Results emphasize the need for further investigation of treatment effects in mammary carcinogenesis in mouse models.

Implication

Observational analysis revealed changes in complement system proteins in irradiated BALB/c mice, suggesting treatment impacts.

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Cite This Study

Akbarzadeh et al. (2025) studied this question.

synapsesocial.com/papers/68af570dad7bf08b1eaddc37 https://doi.org/10.1158/2767-9764.29966131

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure 2 from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis2025
2Figure 1 from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis2025
3Supplementary Figure S1 from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis2025
4Supplementary Figure S2 from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis2025
5Figure 3 from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis2025

Figure 5 from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis2025
Data from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis2025
Plasma proteomic analysis reveals complement system changes in irradiated female BALB/c mice during mammary carcinogenesis2025