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August 24, 2025FoodsOpen Access

An Extensive Analysis of Artemisia integrifolia Linn. on T2DM: Investigating Glycolipid Metabolism, Metabolic Profiling, and Molecular Docking for Potential Functional Food Applications

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Authors

MLMeng LiuFSFazhi SuYHYujia He

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Overview

Observational analysis shows LH improves insulin resistance and glycolipid metabolism in T2DM rats, indicating potential as a functional food.

Key Points

  • LH treatment reduced fasting blood glucose (FBG) levels while increasing body weight, showing its efficacy in managing T2DM.
  • A total of 66 compounds were identified, with key active components including caffeic acid and coumarin, supporting LH’s therapeutic potential.
  • The study utilized UPLC-Q-TOF-MS/MS to profile metabolites and metabolic pathways affected in T2DM, highlighting significant insights for further application.
  • Findings suggest that modulation of the S1P and PI3K/AKT signaling pathways may underlie LH’s beneficial effects on T2DM.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68af5bc7ad7bf08b1eae0158https://doi.org/10.3390/foods14172945
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