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Clinical pharmacologists collaborate on new approach methodologies in drug development, highlighting the importance of reducing animal use.
As new approach methodologies (NAMs) gain regulatory momentum for Investigational new drug (IND) applications, clinical pharmacologists are uniquely positioned to collaborate with preclinical and translational teams in the development, quantification, and implementation of these methodologies. Their involvement is critical to ensuring a reduction in animal use to support early‐phase drug development.
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Cao et al. (2025) studied this question.
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