Case study reveals importance of alkaline phosphatase in identifying prostate cancer, suggesting thorough diagnostics are crucial.
A 60-year-old asymptomatic male was found to have an isolated raised alkaline phosphatase (ALP) level during routine blood tests. Initial liver function investigation, including liver screen and ultrasound, was unremarkable. Further evaluation to identify non-hepatic causes revealed an elevated prostate-specific antigen (PSA). Subsequent investigations confirmed a diagnosis of metastatic prostate cancer with bony involvement, explaining the raised ALP. This case underscores the importance of a thorough diagnostic approach to isolated raised ALP and highlights evidence-based management of suspected prostate cancer.
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Khan et al. (2025) studied this question.
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