Contrast-induced acute kidney injury in patients after thoracic aortic replacement

Introduction . According to modern concepts, the development of contrast-induced acute kidneys injury after endovascular interventions can negatively affect the results of treatment and can also increase the mortality level. Objective . To evaluate the incidence of contrast-induced acute kidney injury and its impact on treatment results of patients after endovascular replacement of the breast department aorta. Materials and methods . The study included 107 patients who underwent endovascular thoracic aortic replacement. Patients were divided into two groups: the first group with contrast induced acute kidney injury patients and the second group where patients were without any renal damages. Every patient was assessed for age, comorbid status, serum creatinine level and glomerular filtration rate (before intervention, after 24, 48, 72 hours and before discharge). The risk of developing CI-AKI was assessed using the R. Mehran scale. Results. Of all the selected patients, CI-AKI was diagnosed in 20 (18.7 %). The amount of patients with concomitant chronic obstructive pulmonary disease (p = 0.04), post-infarction cardiosclerosis (p = 0.05), chronic heart failure (p = 0.02), ejection fraction left ventricle less than 40 % (p = 0.016) and kidney diseases (p = 0.002) in the first group was significantly more than in the second group. According to the results of multivariate regression analysis of independent risk factors for the development of contrast-induced kidney damage were the patient’s age (OR 1.076; 95 % CI [1.00–1.15]; p = 0.0049) and the volume of used contrast used liquid (OR 1.019; 95 % CI [1.01–1.03]; p = 0.001). Conclusion . Despite the high incidence of contrast-induced acute injury kidneys after endoprosthetics of the thoracic aorta the postoperative period for patients can be evaluated as favorable. The patient’s age and contrast volume are the risk factors for the development of the postoperation complications.