Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 2023Ochsner JournalOpen Access

Zero to Hero? Reducing the Rate of Acute Kidney Injury in Transcatheter Aortic Valve Replacement: The Low Contrast Approach

View Full Paper
Ask AI
Bookmark
Share

Why the study?

AKI after TAVR increases hospital stay, morbidity, and mortality, and contrast volume is linked to AKI occurrence. Reducing contrast is hypothesized to decrease AKI without compromising outcomes.

Does low contrast TAVR (≤20 mL) reduce postoperative acute kidney injury in patients undergoing TAVR compared to standard contrast (>20 mL)?

Population

594 patients who underwent TAVR from 2017 to 2019

Comparison

≤20 mL of contrast vs >20 mL of contrast

Design

Single-institution retrospective analysis

Follow-up

30 days

Authors

MGManuel Giraldo-GruesoRBRyan S. BediJSJose Tafur Soto

Discussion

Loading...

Member takes

Overview

Low-contrast TAVR was associated with reduced AKI; leaves open whether this approach improves hard outcomes in randomized trials.

Structured PICO

Does low contrast TAVR (≤20 mL) reduce postoperative acute kidney injury in patients undergoing TAVR compared to standard contrast (>20 mL)?

P
Population
594 patients who underwent transcatheter aortic valve replacement (TAVR) from 2017 to 2019 at a single institution. Excluded: patients with a left ventricular assist device or end-stage renal disease.
I
Intervention
Low contrast TAVR (≤20 mL of contrast)
C
Comparator
Standard contrast TAVR (>20 mL of contrast)
O
Outcome
30-day mortality, postoperative acute kidney injury (AKI), and early aortic regurgitationsafety

A low contrast approach (≤20 mL) during TAVR is safe and feasible, resulting in low rates of acute kidney injury without compromising procedural outcomes or increasing mortality.

Limitations

  • Single institution retrospective analysis without a control group
  • Procedures done by an experienced team that is accustomed to performing low contrast TAVR
  • Long-term results were not analyzed

Cite This Study

Giraldo-Grueso et al. (2023) studied this question.

synapsesocial.com/papers/6a7614a78802f13c0e613bebhttps://doi.org/10.31486/toj.23.0103
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acute kidney injury post–transcatheter aortic valve replacement2017 · 66 citations
  2. 2Acute Kidney Injury in Transcatheter Aortic Valve Replacement2021 · 11 citations
  3. 3Acute kidney injury and outcome following aortic valve replacement for aortic stenosis2016 · 18 citations
  4. 4Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients2019 · 4,902 citations
  5. 5Outcomes 2 Years After Transcatheter Aortic Valve Replacement in Patients at Low Surgical Risk2021 · 327 citations