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April 13, 2023Open Access

Zero To Hero? Reducing The Rate of Acute Kidney Injury in Transcatheter Aortic Valve Replacement: The Low Contrast Approach

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Why the study?

Contrast volume is linked to acute kidney injury after TAVR, and reducing contrast was hypothesized to decrease acute kidney injury without compromising outcomes.

Does a low contrast approach (≤20 mL) reduce acute kidney injury in patients undergoing transcatheter aortic valve replacement?

Population

594 patients undergoing TAVR

Comparison

Contrast 20 mL or less vs contrast more than 20 mL

Design

Single-institution retrospective analysis

Follow-up

30 days

Authors

MGManuel Giraldo-GruesoRBRyan S. BediJSJose Tafur Soto

Discussion

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Member takes

Overview

No significant AKI reduction with low-contrast TAVR; leaves open benefit of further minimization in high-risk patients.

Structured PICO

Does a low contrast approach (≤20 mL) reduce acute kidney injury in patients undergoing transcatheter aortic valve replacement?

P
Population
594 patients undergoing transcatheter aortic valve replacement (TAVR) between 2017 and 2019 at a single institution.
I
Intervention
Low contrast volume (20 mL or less) during TAVR
C
Comparator
Standard/higher contrast volume (more than 20 mL) during TAVR
O
Outcome
30-day mortality, acute kidney injury, and early aortic regurgitationsafety

A low contrast approach (≤20 mL) during TAVR is feasible and safe, though the observed reduction in acute kidney injury compared to >20 mL was not statistically significant in this cohort.

Cite This Study

Giraldo-Grueso et al. (2023) studied this question.

synapsesocial.com/papers/6a8bf00add62e0468bc5d627https://doi.org/10.21203/rs.3.rs-2720633/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Zero to Hero? Reducing the Rate of Acute Kidney Injury in Transcatheter Aortic Valve Replacement: The Low Contrast Approach2023 · 2 citations
  2. 2A Contrast Frugal Approach to Transcatheter Aortic Valve Replacement in Chronic Kidney Disease: A Pilot Study2022 · 1 citations
  3. 3Renal Function–Based Contrast Threshold Predicts Kidney Injury in Transcatheter Aortic Valve Replacement2022 · 13 citations
  4. 4Contrast-free (Zero-contrast) TAVR for Severe Aortic Stenosis in Patient with Chronic Kidney Disease2018 · 4 citations
  5. 5Long‐term outcomes after transcatheter aortic valve replacement with minimal contrast in chronic kidney disease2020 · 2 citations