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August 26, 2025Acta NeuropsychiatricaOpen Access

C-reactive protein is not a biomarker of depression severity in drug-naïve obese patients with metabolic syndrome

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Authors

AAAbbas F. AlmullaUniversidade Estadual de Londrina SKSpas KitovMedical University Plovdiv TDTanya DenevaMedical University Plovdiv

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Implication

Observational analysis shows no link between c-reactive protein and depression severity in obese patients with metabolic syndrome, suggesting other biomarkers are involved.

Key Points

Depressive symptoms are not associated with c-reactive protein levels, indicating it may not be a reliable depression biomarker.
Increased severity of depression was linked to interleukin-6, triglyceride x glucose index, and other immune-metabolic biomarkers.
Assessment involved 88 drug-naïve obese patients with metabolic syndrome, focusing on various serum biomarkers.
Findings highlight the role of immune activation and insulin resistance in depression among obesity-metabolic syndrome patients, excluding hsCRP.

Cite This Study

Almulla et al. (2025) studied this question.

synapsesocial.com/papers/68af63e9ad7bf08b1eae47cf https://doi.org/10.1017/neu.2025.10034

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Implication

Observational analysis shows no link between c-reactive protein and depression severity in obese patients with metabolic syndrome, suggesting other biomarkers are involved.

C-reactive protein is not a biomarker of depression severity in drug-naïve obese patients with metabolic syndrome

Discussion

Member takes

Implication

Key Points

Cite This Study

C-reactive protein is not a biomarker of depression severity in drug-naïve obese patients with metabolic syndrome

Discussion

Member takes

Implication

Key Points

Cite This Study

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