A Rare Case of Recurrent Cervical Lymphadenitis: Kimura Disease in a Male Child and Literature Review

Kimura disease (KD), or eosinophilic hyperplastic lymphoid granuloma, is an uncommon chronic inflammatory condition presented with a painless subcutaneous head-and-neck swelling. KD is associated with intermittent fever, increased eosinophils, and elevated serum immunoglobulin E levels. Because KD is uncommon in clinical practice, especially in children, it frequently leads to misdiagnosis or a missed diagnosis in pediatric patients. The primary modes of treatment have been detailed in numerous papers; corticosteroids and surgery have both produced positive outcomes; however, corticosteroids occasionally cannot be reduced as the condition flares up. Here, we describe a 7-year-old boy who presented to us with recurrent cervical lymphadenitis, treated three times with multiple antibiotics, and later on diagnosed to be a case of KD. After the exclusion of infectious causes by biochemical and hematological investigation, finally, KD was diagnosed by histopathology. Although steroid was a successful treatment in this case to start with, the tumor recurred shortly after the drug dose was tapered. Hence, we started cyclosporine along with steroids as a treatment regimen.