Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 5, 2025European journal of medical researchOpen Access

The association of metabolic syndrome with aortic aneurysm: a two-sample Mendelian randomization study

View Full Paper
Ask AI
Bookmark
Share

Authors

CLChaodi LuoYZYiting ZhaoJZJing Zhang

Discussion

Loading...

Member takes

Overview

Mendelian randomization analysis reveals a significant link between metabolic syndrome and aortic aneurysm, suggesting critical cardiovascular implications.

Key Points

  • Genetically predicted metabolic syndrome significantly increases the risk of aortic aneurysm (OR: 1.308).
  • Components of metabolic syndrome, like body mass index and triglycerides, are major risk factors for aortic aneurysm.
  • Mendelian randomization analysis using various methods solidified the causality findings about metabolic syndrome and aortic aneurysm.
  • Elevated blood pressure and specific metabolic syndrome components were identified as risk factors, except for high blood glucose and type 2 diabetes.

Cite This Study

Luo et al. (2025) studied this question.

synapsesocial.com/papers/68bb3d4e2b87ece8dc955a36https://doi.org/10.1186/s40001-025-03094-1
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Causality of the Metabolic Syndrome and its Ingredients on Cardiovascular Disease: A Two-sample Mendelian Randomization Analysis2026
  2. 2Causal Inference of Metabolic Syndrome on Calcific Aortic Valve Stenosis: Linkage Disequilibrium Score Regression and Two-Sample, Two-Step Mendelian Randomization Analysis2025
  3. 3Causal inference and mediating pathways of metabolic syndrome on calcific aortic valve stenosis: linkage disequilibrium score regression and two-sample, two-step mendelian randomization study2026
  4. 4Causality of genetically determined serum metabolites on thoracic and abdominal aortic aneurysm: Mendelian randomization study2025 · 2 citations
  5. 5Mendelian randomization analysis of the causal relationship between serum metabolites and thoracic aortic aneurysm2024