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September 5, 2025Journal of Clinical MedicineOpen Access

The Effect of Aerobic Exercise Training on Patients with Type III Spinal Muscular Atrophy

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Authors

SKSezan Mergen KılıçFMFatma MutluayAÇArman Çakar

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Overview

Observational analysis reveals improvements in exercise capacity and muscle strength in SMA type III patients, indicating aerobic exercise as an effective adjunct therapy.

Key Points

  • Aerobic exercise training significantly improved exercise capacity in SMA type III patients, enhancing their physical function.
  • The study reported a notable increase in 6-minute walk test scores, with p-values indicating strong statistical significance (p < 0.001).
  • Patients engaged in a 12-week aerobic exercise program showed increased serum levels of survival motor neuron protein and IGF-1 hormone, enhancing their biochemical status.
  • Further research may support aerobic exercise as a beneficial adjunct therapy, promoting functional improvements alongside traditional treatments.

Cite This Study

Kılıç et al. (2025) studied this question.

synapsesocial.com/papers/68bb3ef72b87ece8dc957a98https://doi.org/10.3390/jcm14176087
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Also Consider

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  1. 1Physical exercise training for type 3 spinal muscular atrophy2019 · 64 citations
  2. 2Effects of physical therapy on motor ability in patients with spinal muscular atrophy III: a study protocol for a randomised controlled trial2025
  3. 3Effects of physical therapy on motor ability in patients with spinal muscular atrophy III: a study protocol for a randomised controlled trial2025
  4. 4Drug treatment for spinal muscular atrophy types II and III2012 · 100 citations
  5. 5Resistance strength training exercise in children with spinal muscular atrophy2015 · 107 citations